Background:

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]

Applications:

WB

Name of antibody:

NMI

Immunogen:

Fusion protein of human NMI

Full name:

N-myc and STAT interactor

SwissProt:

Q13287

WB Predicted band size:

35 KD

WB Positive control:

K562 cell lysate

WB Recommended dilution:

500-2000