Background: | NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008] |
Applications: | WB |
Name of antibody: | NMI |
Immunogen: | Fusion protein of human NMI |
Full name: | N-myc and STAT interactor |
SwissProt: | Q13287 |
WB Predicted band size: | 35 KD |
WB Positive control: | K562 cell lysate |
WB Recommended dilution: | 500-2000 |